Bodo Glimt 0-1 Arsenal
• Pencetak gol: Bukayo Saka (24')
PSV Eindhoven 5-0 FC Zurich
• Pencetak gol: Erick Gutierrez (9'), Joey Veerman (15'), (55'), Ibrahim Sangare (34'), Anwar El Ghazi (84')
Grup B
Dynamo Kiev 0-1 Rennes
• Pencetak gol: Christopher Wooh (48')
AEK Larnaca 1-2 Fenerbahce
• Pencetak gol: Ivan Trickovski (pen 52') - Joao Pedro (16'), Michy Batshuayi (pen 80')
Grup C
Real Betis 1-1 AS Roma
• Pencetak gol: Sergio Canales (34') - Andrea Belotti (53')